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Image Search Results
Journal: International Journal of Clinical and Experimental Pathology
Article Title: WDR1 predicts poor prognosis and promotes cancer progression in hepatocellular carcinoma
doi:
Figure Lengend Snippet: WDR1 was significantly upregulated and associated with metastasis in HCC. (A, B) mRNA (A) and protein (B) expression of WDR1 were upregulated in HCC cell lines compared with normal liver cell line L02, as detected by qRT-PCR and WB. (C) WDR1 mRNA expression was higher in 30 snap-frozen HCC tissues than in matched adjacent nontumorous liver tissues (ANLTs). (D) The representative Western-blotting pictures of protein expression of WDR1 in four paired snap-frozen HCC tissues and matched ANLTs. (E) HCC exhibited a higher WDR1 expression than corresponding ANLTs by IHC. Left panel: Representative IHC staining of WDR1 in ANLT and HCC, Magnification: left: 100 ×, right: 400 ×.; Right panel: Box-plot analyzing the immunohistochemical scores in HCC tissues and ANLTs. (F) WDR1 mRNA expression was significantly higher in tumors with microvascular invasion (MVI), advanced stage (TNM II/III) and early recurrence (ER, within 2 years) than those without MVI (NMVI), with early stage (TNM I), and without early recurrence (NER) respectively. *P < .05, **P < .01, ***P < .001.
Article Snippet: 30 pairs of frozen
Techniques: Expressing, Quantitative RT-PCR, Western Blot, Immunohistochemistry, Immunohistochemical staining